The central competent authority may refuse or reject an application, if document sent for application of registration approval by the applicants meets any of the following circumstances:
1. The registrant fails to submit information through registration tool designated by the central competent authority, or fill out corresponding forms
2. Registration fees are failed to be paid according to the application fee standard.

The central competent authority shall review the document sent for registration approval application by an applicant.
For the review procedure pursuant to the previous paragraph, the central competent authority shall invite experts and scholars specialized in relevant fields, and set up a review panel.

The central competent authority shall review assessment reports; should the review procedure finds that information mistaken or inadequate, the central competent authority shall require the registrant to make supplementation and correction.
The applicant shall make supplementation and correction within 30 working days of receiving the notification of supplementation and correction.
Registration review shall be deemed not approved if the registrant fails to make supplementation and correction within the allotted time. Correction and supplementation pursuant to the previous paragraph shall only be made no more than twice.

If an applicant has any concerns regarding the result of registration review, written appeal with stated reasons may be submitted within 30 working days after receiving the notification of review results.
The appeal pursuant to the previous paragraph shall be made once only.

An applicant shall keep all the documents submitted through registration tools and the registration approval document for five years.

The central competent authority may commission related professional organizations to carry out procedures of new chemical substances registration approval.

The central competent authority shall issue registration approval document where assessment reports submitted by an applicant meet applicable requirements after review.

The following items shall be specified in the a registration approval document:
1. Registrant basic information
2. New chemical substance serial number
3. Approved registration type
4. Document issue date and valid period